SPECTRAL, REDOX AND BIOLOGICAL CHARACTERIZATION OF
NEWLY SYNTHESIZED Co(II) AND Ni(II) COMPLEXES OF AMPYRONE
AND OXALATE ION

K. Rajasekar1, K. Kanagaraj2, S. Naveen Kumar2, R. Rajiv Ganthi2 ,R. Rajkumar2
Page No. 9-16

Transition metal ions are easily form complexes due to the presence of vacant d orbital and more
positive character of that metal ion. Complexes of Co(II) and Ni(II) with ampyrone and oxalate ion
have been prepared and characterized by metal estimation, molar conductance, UV-visible
spectra, IR-spectra, redox property (cyclic voltammetry) and biological activities. From the results
of metal estimation and molar conductance, the general formula of the complex is [M(L1)4(X)]
where M is Co(II) and Ni(II), L is ampyrone (monodentate) and X is oxalate ion (bidentate). The
metal ligand ratio is 1:2:1 and it is non-electrolyte, neutral complexes. The magnetic moment and
UV-visible spectral data of the complexes confirm the octahedral geometry around the metal ion.
The results of IR spectra of the ligands and its complexes show the coordination atom is nitrogen of
ampyrone and oxygen of oxalate ion. Redox property of Ni(II) complex from cyclic voltammeter
exhibit quasi reversible one electron transfer reaction. The antibacterial and antifungal activities of
ampyrone and its complexes were tested against E. coli, P. aeruginosa, K. Pnemonia and A. Niger
(Fungus) by Agar well diffusion methods. The results indicate that the complexes are more active
than the ampyrone.
Key Words: Ampyrone, Oxalate ion, Cyclic voltammeter, Antibacterial, Antifungal.