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CAUSES OF INFERLITY


Ms.Cameliya Mukherjee,
Page No. 84-89


Abstract

Infertility is a common problem affecting one couple in six. It can be defined as the incapacity to
fulfill pregnancy after reasonable time of sexual intercourse with no contraceptive measures
taken.Male and female infertility affects close to 50 million couples worldwide according to a
recent World Health Organization estimate. Many of the 25-30% of couples with idiopathic
infertility likely have a geneticetiology for their condition. Genetic and genomic causes of infertility
can be divided into cytogenetic anomalies, gene defects, and epigenetic aberrances. During the past
two decades there have been three important changes in infertility practice. First, the introduction
of assisted reproduction technologies has provided an opportunity to study basic reproductive
processes. Second, societal changes have occurred such as the increase in the proportion of women
over 35 years old seeking pregnancy. This fact is due to a later age for marriage and postponement
of pregnancy. Third, the development of molecular biology and genetics has become very important
for the study, diagnosis and assessment of couples, many of them considered until now as
“unexplained infertile couples”.
Keywords : Infertility, spermatogenesis, oogenesis


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