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Nephropathies and pregnancies: about a series of 17 cases.


FASSIL Sara*, FADILI Wafaa, LAOUAD Inass.
Page No. 8-15


Abstract

Introduction: The association of nephropathy and pregnancy represents a situation at high risk of
complications. The aim of the work is to analyze the clinical, histological and prognostic data of 17
patients with renal impairment during pregnancy; collected in the nephrology department of
Marrakech. Results: The average age is 27 years. The mode of discovery is nephrotic syndrome in 6
cases and renal failure in 7 cases. The renal biopsy puncture is performed in 12 patients. The
histological study showed two cases of extra-membranous glomerulonephritis, one case of chronic
interstitial tubulo nephritis, one patient with lupus nephropathy, and histological signs of
preeclampsiae a patient, extra-capillary glomerulonephritis in one patient, and cortical necrosis in
one patient. one case, membranous proliferative glomerulonephritis in one case, segmental and
focal hyalinosis in two cases, glomerulosclerosis in one patient, and IgA nephropathy in one case.
Obstetrically, a therapeutic termination of pregnancy is indicated in 3 cases, a cesarean section for
maternal rescue is performed in 3 patients. 5 out of 14 deliveries are premature. With 3 neonatal
deaths and one intrauterine fetal death. The evolution is marked by the installation of a chronic
renal insufficiency in 4 cases whereas it is terminal at home 3 cases. In addition, a favorable
evolution is noted in 8cas. Conclusion: Any pregnancy in a woman with nephropathy is a high-risk
pregnancy; and that must be planned and followed.
Keywords : Pregnancy - renal failure - proteinuria - preeclampsia - maternal-fetal complications


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