KNOWLEDGE ATTITUDES AND PRACTICES OF AFRICAN DOCTORS
TO REACTIVATION VIRAL B IN THE COURSE OF CHEMOTHERAPY

Mongo-onkouoA (1 ,2), Diané S3,Ahoui Apendi C P(1,2), Mimiesse Monamou J F(1 ,2), Olandzobo
Ikobo L C (2, 4), Atipo-ibara B I(1,2), Deby Gassay (1,2),Ngalessami Mouakosso1M, Itouangaporo
1 N, Adoua C S 1, Ibara J R(1,2)
Page No. 25-29

Patients treated with chemotherapy for hematological or cancerous pathology have a risk of
reactivation of hepatitis B virus (HBV). There is no data on viral reactivation B in Africa. The
purpose of this work is to evaluate the knowledge and practices of African physicians on HBV
testing during chemotherapy. Materials and methods: This was a prospective survey carried out
from 04/05/2016 to 06/05/2016 at the VIIth Euro-African Congress of Oncology in Yaoundé. A preestablished
questionnaire was provided to African prescribers of chemotherapy. The items in the
survey included screening, knowledge of the viral hepatitis B profile, recommendations on viral
reactivation B, treatment and physician experience. on viral reactivation B.Results: We interviewed
200 African doctors, 83 doctors answered either a participation rate of 41.5%. They came from 11
French-speaking African countries. There were 68 (81.9%) medical oncologists, the other
participants were 15 or 18.1% of respondents. 47 (56.6%) physicians have no knowledge of
reactivation of HBV. However, 6 (7.2%) physicians observed a case of viral reactivation.69 (83.1%)
of the respondents do not know that there are recommendations on HBV screening before
chemotherapy. As a result, the majority of respondents did not answer the question about the
incriminated molecules in viral reactivation B.5 3 (63.9%) doctors recognize the high risk of
reactivation for the patient profile cured and51 (61.4%) doctors for the patient chronic carrier. In
contrast, 9 (10.8%) treat high-risk patients; 74 (89.2%) doctors do not do prophylaxis and 70
doctors (84.3%) do not vaccinate patients with HBV seronegative profile.Conclusion: knowledge of
African doctors about viral reactivation is incomplete, practices and the attitudes of practitioners
are inadequate.
Keywords : Reactivation B virus, chemotherapy.